Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651267 | 0.90 | CYP11B1 (0.45) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10649902 | 0.76 | CYP1A2 (0.66) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL10653023 | 0.76 | PDE3B (0.46) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10649858 | 0.76 | NOS1 (0.51) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10651166 | 0.74 | CYP11B1 (0.50) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10649864 | 0.74 | CYP11B1 (0.52) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2457137 | 0.73 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL11121633 | 0.73 | CA12 (0.49) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11121622 | 0.73 | CA12 (0.49) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13325933 | 0.73 | SMN1; SMN2 (0.60) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120589-B1 | IMIDAZO-HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4621084-A | CARDIOTONIC, ANTIULCER | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0120589-A1 | Imidazo-heterocyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |