Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | NQO2 | P16083 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654879 | 0.81 | ACHE (0.40) | CYP19A1NQO2MEN1KMT2AALDH1A1 | |
| SCHEMBL10565244 | 0.81 | MAPT (0.47) | CYP19A1NQO2MEN1KMT2AALDH1A1 | |
| SCHEMBL10565240 | 0.81 | MAPT (0.47) | CYP19A1NQO2MEN1KMT2AALDH1A1 | |
| SCHEMBL21621341 | 0.76 | PDE3B (0.36) | MEN1KMT2AALDH1A1ABCC4ABCC5 | |
| SCHEMBL10655760 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL10655756 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL10571122 | 0.70 | CYP3A4 (0.54) | AMY1ACYP19A1NQO2HDAC4HDAC2 | |
| SCHEMBL10571125 | 0.70 | CYP3A4 (0.54) | AMY1ACYP19A1NQO2HDAC4HDAC2 | |
| SCHEMBL10566825 | 0.64 | MAPT (0.50) | MEN1KMT2AALDH1A1ABCC4ABCC5 | |
| SCHEMBL10566820 | 0.64 | MAPT (0.50) | MEN1KMT2AALDH1A1ABCC4ABCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |