Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565240 | 0.86 | MAPT (0.47) | CYP19A1NQO2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10565244 | 0.86 | MAPT (0.47) | CYP19A1NQO2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10651365 | 0.81 | AMY1A (0.39) | CYP19A1NQO2ALDH1A1KMT2AMAPT | |
| SCHEMBL10655756 | 0.81 | ALDH1A1 (0.46) | GSK3BALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL10653538 | 0.73 | CCNB2 (0.48) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL21621341 | 0.72 | PDE3B (0.36) | ALDH1A1KMT2AMAPTLMNAHTT | |
| SCHEMBL10566842 | 0.68 | MAPK1 (0.54) | ACHEBRD4CYP19A1NQO2ALDH1A1 | |
| SCHEMBL10566848 | 0.68 | MAPK1 (0.54) | ACHEBRD4CYP19A1NQO2ALDH1A1 | |
| SCHEMBL10566820 | 0.66 | MAPT (0.50) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL10564671 | 0.65 | MAPT (0.57) | ALDH1A1KDM4EKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |