SCHEMBL1065215

SCHEMBL1065215

CC(=O)NNC(=O)C[C@@H](O)C[C@@H](C)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.31
CYP2C9 P11712 1/20 0.31
GAA P10253 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KISS1R Q969F8 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365359 0.76 ALDH1A1 (0.48) ALDH1A1GAALMNASMN1; SMN2KISS1R
SCHEMBL3512468 0.73 ALDH1A1 (0.50) ALDH1A1KISS1RTDP1
SCHEMBL7567721 0.73 ALDH1A1 (0.50) ALDH1A1KISS1RTDP1
SCHEMBL14430862 0.73 ALDH1A1 (0.50) ALDH1A1KISS1RTDP1
SCHEMBL17066345 0.73 ALDH1A1 (0.50) ALDH1A1KISS1RTDP1
SCHEMBL10661813 0.72 ALDH1A1 (0.48) ALDH1A1KISS1RTDP1
SCHEMBL24184026 0.71 GABRR1 (0.37) ALDH1A1SMN1; SMN2TDP1
SCHEMBL976030 0.69 SLC22A6 (0.60) LMNASMN1; SMN2TDP1
SCHEMBL8292735 0.69 SLC22A6 (0.60) LMNASMN1; SMN2TDP1
SCHEMBL976447 0.69 SLC22A6 (0.60) LMNASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2994161-B1 PROBIOTIC PREVENTION AND TREATMENT OF COLON CANCER CALIFORNIA INST OF TECHN (US) 2020-10-28 EP claimed
US-10772918-B2 Probiotic prevention and treatment of colon cancer CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2020-09-15 US claimed
US-20190336545-A1 Probiotic Prevention and Treatment of Colon Cancer CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-11-07 US claimed
WO-2023147504-A1 POLYSACCHARIDE A-BASED PARTICULATE SYSTEMS FOR ATTENUATION OF AUTOIMMUNITY, ALLERGY, AND TRANSPLANT REJECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-03 WO disclosed
US-11622973-B2 Immunomodulating compounds and related compositions and methods CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-04-11 US disclosed
US-11419887-B2 Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-08-23 US disclosed
US-11331335-B2 Sepsis treatment and related compositions methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-05-17 US disclosed
EP-2994161-B1 PROBIOTIC PREVENTION AND TREATMENT OF COLON CANCER CALIFORNIA INST OF TECHN (US) 2020-10-28 EP disclosed
US-10772918-B2 Probiotic prevention and treatment of colon cancer CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2020-09-15 US disclosed
US-10765696-B2 Compositions of and methods of treatment with zwitterionic polysaccharide CITY OF HOPE (US) 2020-09-08 US disclosed
US-20200197436-A1 Immunomodulating Compounds and Related Compositions and Methods BRIGHAM AND WOMEN'S HOSPITAL 2020-06-25 US disclosed
US-20130064859-A1 COMBINATORIAL VITAMIN D AND PROBIOTIC THERAPY FOR INFLAMMATORY BOWEL DISEASE CALIFORNIA INSTITUTE OF TECHNOLOGY 2013-03-14 US disclosed
US-20130039949-A1 IMMUNOMODULATING COMPOUNDS AND RELATED COMPOSITIONS AND METHODS MAZMANIAN SARKIS (US) 2013-02-14 US disclosed
EP-2555753-A2 VEHICLE FOR DELIVERING A COMPOUND TO A MUCOUS MEMBRANE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS Shen, Yue (US) 2013-02-13 EP disclosed
WO-2012103532-A1 COMBINATORIAL VITAMIN D AND PROBIOTIC THERAPY FOR INFLAMMATORY BOWEL DISEASE MAZMANIAN SARKIS K (US) 2012-08-02 WO disclosed
US-20110287048-A1 Antigen Specific Tregs and related compositions, methods and systems NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-11-24 US disclosed
WO-2011127302-A2 VEHICLE FOR DELIVERING A COMPOUND TO A MUCOUS MEMBRANE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS SHEN YUE (US) 2011-10-13 WO disclosed
US-20110251156-A1 VEHICLE FOR DELIVERING A COMPOUND TO A MUCOUS MEMBRANE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS NATIONAL INSTITUTES OF HEALTH 2011-10-13 US disclosed
US-20110002965-A1 IMMUNOMODULATING COMPOUNDS AND RELATED COMPOSITIONS AND METHODS NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2011-01-06 US disclosed
US-20090124573-A1 IMMUNOMODULATING COMPOUNDS AND RELATED COMPOSITIONS AND METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-05-14 US disclosed