Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292735 | 1.00 | SLC22A6 (0.60) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL976030 | 1.00 | SLC22A6 (0.60) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL667024 | 0.84 | SLC22A6 (0.60) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL4748781 | 0.84 | SLC22A6 (0.60) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL6453593 | 0.83 | SLC22A6 (0.75) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL16600216 | 0.80 | SLC22A6 (0.55) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL19615565 | 0.80 | SLC22A6 (0.36) | SLC22A6GABRR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL14189817 | 0.80 | SLC22A6 (0.55) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL13701365 | 0.80 | SLC22A6 (0.55) | SLC22A6GABRR1MAPTLMNAGPR84 | |
| SCHEMBL28670099 | 0.80 | SLC22A6 (0.55) | SLC22A6GABRR1MAPTLMNAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112662637-A | Formate dehydrogenase mutant and preparation method and application thereof | 江苏阿尔法药业有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-104789505-B | Reduction prepares the method and strain of cis 3,5 dihydroxyhexanoate compound | 苏州东和盛昌生物科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-104342410-B | Ketone reductase mutant and preparation method thereof | 南京朗恩生物科技有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-101528917-B | Compositions and methods for preparing stereoisomerically pure statins and synthetic intermediates thereof | CODEXIS, INC. (US) | 2015-07-29 | — | — | CN | claimed |
| CN-104789505-A | Method and strain for preparing cis-3,5-dihydroxyhexanoate compound by reduction and strain | SUZHOU DONGHESHENGCHANG BIOTECHNOLOGY CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-104342410-A | Ketone reductase mutant and preparation method thereof | NANJING LANG EN BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-02-11 | — | — | CN | claimed |
| EP-2066788-B1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS INC (US) | 2014-07-23 | — | — | EP | claimed |
| US-8273547-B2 | Engineered ketoreductases and methods for producing stereoisomerically pure statins | CODEXIS, INC. (US) | 2012-09-25 | — | — | US | claimed |
| EP-2240442-B1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA CO LTD (KR) | 2012-06-20 | — | — | EP | claimed |
| US-20110195465-A1 | Compositions and Methods for Producing Stereoisomerically Pure Statins and Synthetic Intermediates Therefor | CODEXIS, INC. (US) | 2011-08-11 | — | — | US | claimed |
| US-7879585-B2 | Ketoreductases of Saccharomyces cerevisiae; host cells | CODEXIS, INC. (US) | 2011-02-01 | — | — | US | claimed |
| EP-2066788-A2 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | Codexis, Inc. (US) | 2009-06-10 | — | — | EP | claimed |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-10-09 | — | — | US | claimed |
| WO-2008042876-A2 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-04-10 | — | — | WO | claimed |
| EP-1439162-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3,5-DIHYDROXYCARBOXYLIC ACID DERIVATIVE | KANEKA CORP (JP) | 2008-03-26 | — | — | EP | claimed |
| US-6998495-B2 | Method for producing optically active 3,5-dihydroxycarboxylic acid derivative | KANEKA CORPORATION (JP) | 2006-02-14 | — | — | US | claimed |
| US-20040254392-A1 | Process for producing optically active 3,5-dihydroxycarboxylic acid derivative | KANEKA CORPORATION (JP) | 2004-12-16 | — | — | US | claimed |
| EP-1439162-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3,5-DIHYDROXYCARBOXYLIC ACID DERIVATIVE | KANEKA CORPORATION (JP) | 2004-07-21 | — | — | EP | claimed |
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | HERCULES CAPITAL, INC. | 2025-04-24 | — | — | US | disclosed |
| US-5286883-A | (3R,5S)-3,5,6-trihydroxyhexanoic acid derivative and production method thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254392-A1 | Process for producing optically active 3,5-dihydroxycarboxylic acid derivative | HAO2, GRHPR, HDHD5 | SLC22A6 4289/4885GABRR1 196/4885MAPT 4530/4885 |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | COASY, FAR1, HMGCR | SLC22A6 2136/4885GABRR1 724/4885MAPT 3851/4885 |
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | CSGALNACT1, CHI3L2, LNPEP | SLC22A6 312/4885GABRR1 3518/4885MAPT 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.