⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599193 | 0.81 | — | — | |
| SCHEMBL11215633 | 0.74 | MGLL (0.41) | — | |
| SCHEMBL11196936 | 0.73 | — | — | |
| SCHEMBL17599206 | 0.70 | — | — | |
| SCHEMBL2299255 | 0.69 | HEXA (0.31) | — | |
| SCHEMBL17599200 | 0.68 | HEXA (0.33) | — | |
| SCHEMBL11221601 | 0.67 | SIGMAR1 (0.32) | — | |
| SCHEMBL2037670 | 0.64 | — | — | |
| SCHEMBL17599195 | 0.63 | — | — | |
| SCHEMBL8465143 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | claimed |
| EP-0251143-A1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0200159-A2 | 3-Acylamino-2-oxo-1-azetidinesulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0177940-A2 | Hydrazine derivatives and their use | E.R. Squibb & Sons, Inc. (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0138407-A1 | Azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0127177-A2 | [[(3-Acylamino-2-oxo-1-azetidinyl)oxy]methyl]phosphinic acids | E.R. Squibb & Sons, Inc. (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0124123-A1 | 3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |