Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648014 | 0.70 | PDE3B (0.41) | — | |
| SCHEMBL10646469 | 0.66 | POLB (0.35) | KMT2AL3MBTL1 | |
| SCHEMBL11115052 | 0.63 | SIGMAR1 (0.41) | SIGMAR1MEN1KMT2A | |
| SCHEMBL18331573 | 0.60 | NOTUM (0.40) | MEN1KMT2A | |
| SCHEMBL30747594 | 0.60 | ADORA2A (0.33) | — | |
| SCHEMBL10648447 | 0.58 | CYP1A2 (0.41) | MEN1KMT2A | |
| SCHEMBL10649242 | 0.58 | TSHR (0.40) | — | |
| SCHEMBL18914239 | 0.58 | PLD1 (0.51) | SIGMAR1L3MBTL1 | |
| SCHEMBL3939957 | 0.58 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10648079 | 0.57 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128502-B1 | SUBSTITUTED 6-(THIEN-2-YL)-3(2H)-PYRIDAZINONES AND PROCESSES FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1988-08-31 | — | — | EP | disclosed |