⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650548 | 1.00 | — | — | |
| SCHEMBL363514 | 1.00 | — | — | |
| SCHEMBL1066789 | 1.00 | — | — | |
| SCHEMBL16098247 | 0.96 | — | — | |
| Acetone SCHEMBL27831020 | 0.93 | LMNA (0.43) | — | |
| Thiourea SCHEMBL7105732 | 0.84 | TSHR (0.35) | — | |
| Ethylenediamine SCHEMBL4854643 | 0.84 | GABRR1 (0.40) | — | |
| SCHEMBL29281365 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL10800909 | 0.82 | TRPA1 (0.38) | — | |
| SCHEMBL27818771 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204324-A1 | Optically Active N-(Alpha-Mercaptopropionyl)Glycine | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2010-08-12 | — | — | US | claimed |
| EP-2181984-A1 | AN OPTICALLY ACTIVE N- (alpha-MERCAPTOPROPIONY) GLYCINE | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2010-05-05 | — | — | EP | claimed |
| US-20260130893-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2026-05-14 | — | — | US | disclosed |
| WO-2026089992-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250376484-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-11 | — | — | US | disclosed |
| WO-2025245003-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| WO-2025202889-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2025-10-02 | — | — | WO | disclosed |
| US-20250154172-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2025-05-15 | — | — | US | disclosed |
| WO-2025096589-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-4749804-A | Preparation of stereoisomers of ketals | SYNTEX (U.S.A.) INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4736061-A | Process for preparing naproxen | BLASCHIM S.P.A. (IT) | 1988-04-05 | — | — | US | disclosed |
| EP-0163338-B1 | PROCESS FOR PREPARING NAPROXEN | Nobel Chemicals AB (SE) | 1987-09-09 | — | — | EP | disclosed |
| US-4670603-A | Process for the preparation of aryl alkyl ketones | BLASCHIM S.P.A. (IT) | 1987-06-02 | — | — | US | disclosed |
| US-4605758-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1986-08-12 | — | — | US | disclosed |
| EP-0176142-A2 | Process for the preparation of aryl alkyl ketones | Nobel Chemicals AB (SE) | 1986-04-02 | — | — | EP | disclosed |
| EP-0163338-A1 | Process for preparing naproxen | Nobel Chemicals AB (SE) | 1985-12-04 | — | — | EP | disclosed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | disclosed |
| EP-0039025-A1 | Derivatives of aryl ketones as sensitizers of photopolymerizable compounds for the visible spectral range, and photopolymerizable compositions comprising the said sensitizers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-04 | — | — | EP | disclosed |