Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738968 | 0.84 | ALDH1A1 (0.35) | OPRD1KCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL10652225 | 0.82 | ALDH1A1 (0.32) | OPRD1KCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL10653165 | 0.78 | RARA (0.39) | ALDH1A1MAPTHPGDRARARARB | |
| SCHEMBL14031140 | 0.75 | PKM (0.33) | OPRD1KCNH2OPRK1 | |
| SCHEMBL10855574 | 0.75 | HTT (0.43) | KCNH2ALDH1A1CYP2D6 | |
| SCHEMBL10855580 | 0.75 | GAA (0.45) | ALDH1A1MAPTCYP2D6KDM4E | |
| SCHEMBL7032951 | 0.74 | PPIB (0.40) | ALDH1A1MAPTHPGDGLAKDM4E | |
| SCHEMBL6535545 | 0.73 | ALDH1A1 (0.41) | OPRD1KCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL27313326 | 0.72 | ALDH1A1 (0.37) | OPRD1KCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL28075539 | 0.72 | ALDH1A1 (0.35) | OPRD1KCNH2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |
| US-4382951-A | FUNGICIDES | SANDOZ LTD. (CH) | 1983-05-10 | — | — | US | disclosed |