Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL4135702 | 0.98 | GPR84 (0.58) | GPR84FFAR1FFAR4ALDH1A1ALOX15 | |
| Phthalic Acid SCHEMBL10653166 | 0.92 | ALDH1A1 (0.58) | GPR84FFAR1FFAR4ALDH1A1ALOX15 | |
| Phthalic Acid SCHEMBL28433236 | 0.92 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Sebacic Acid SCHEMBL8362100 | 0.92 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL11906025 | 0.90 | ALDH1A1 (0.56) | GPR84FFAR1FFAR4ALDH1A1ALOX15 | |
| Phthalic Acid SCHEMBL1906918 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL6742736 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC8MAPTHPGD | |
| Phthalic Acid SCHEMBL28590170 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC8MAPTHPGD | |
| Phthalic Acid SCHEMBL29882947 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC8MAPTHPGD | |
| Phthalic Acid SCHEMBL31192171 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC8MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440605-B | A kind of polylactic resin | 中国科学院长春应用化学研究所 | 2018-01-12 | — | — | CN | disclosed |