Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079176 | 0.80 | CA1 (0.37) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL10649367 | 0.80 | KDM4E (0.36) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL8895550 | 0.79 | MEN1 (0.34) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL10860123 | 0.79 | ACE (0.42) | KDM4EALDH1A1 | |
| SCHEMBL10545523 | 0.78 | CA1 (0.38) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL11293989 | 0.78 | IRAK4 (0.36) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL11470502 | 0.76 | SDCBP (0.35) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| Pyridine SCHEMBL10680880 | 0.73 | ALDH1A1 (0.34) | IRAK4KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL11414269 | 0.73 | KMT2A (0.43) | KDM4EALDH1A1MAPTTHRBHSD17B10 | |
| SCHEMBL11415414 | 0.73 | ACE (0.35) | IRAK4KDM4EALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123442-B1 | IMPROVEMENTS IN OR RELATING TO A PROCESS FOR PRODUCING BETA-LACTAM COMPOUNDS | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4675399-A | N-HYDROXY-2-AZETIDINONES; ACYLATION, SOLVOLYSIS | NOTRE DAME UNIVERSITY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |