Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697627 | 0.82 | CES2 (0.39) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL285026 | 0.82 | CA2 (0.48) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL658242 | 0.81 | CES1 (0.41) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1271166 | 0.77 | CES1 (0.50) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL17030432 | 0.77 | ELANE (0.36) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6679191 | 0.74 | CES2 (0.46) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL26929048 | 0.74 | CES2 (0.46) | CES2CES1MAPTSMN1; SMN2TSHR | |
| SCHEMBL14294140 | 0.74 | ELANE (0.34) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9222482 | 0.72 | CES2 (0.45) | CES2CES1MAPTLMNATSHR | |
| SCHEMBL21243039 | 0.72 | LMNA (0.47) | CES2CES1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268307-A2 | New starting compounds for cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |