Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856504 | 0.88 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAPOLBADORA2BMEN1 | |
| SCHEMBL10653610 | 0.86 | LMNA (0.67) | SMN1; SMN2LMNAPOLBADORA2BMAPT | |
| Water SCHEMBL10856790 | 0.85 | LMNA (0.65) | SMN1; SMN2LMNAPOLBADORA2BMAPT | |
| SCHEMBL20161775 | 0.85 | LMNA (0.77) | SMN1; SMN2LMNAPOLBADORA2BMAPT | |
| SCHEMBL13944619 | 0.85 | LMNA (0.81) | SMN1; SMN2LMNAPOLBADORA2BMAPT | |
| Water SCHEMBL10856780 | 0.84 | LMNA (0.51) | SMN1; SMN2LMNAPOLBADORA2BMEN1 | |
| (S)-Proxyphylline SCHEMBL35570 | 0.83 | LMNA (1.00) | SMN1; SMN2LMNAPOLBADORA2BMEN1 | |
| Proxyphylline SCHEMBL35569 | 0.83 | LMNA (1.00) | SMN1; SMN2LMNAPOLBADORA2BMEN1 | |
| SCHEMBL11601258 | 0.83 | LMNA (0.78) | SMN1; SMN2LMNAPOLBADORA2BMAPT | |
| SCHEMBL11830512 | 0.82 | LMNA (0.77) | SMN1; SMN2LMNAPOLBADORA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089028-B1 | THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-05-25 | — | — | EP | disclosed |