Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | POLB | P06746 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653590 | 1.00 | HCAR2 (0.62) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL27712545 | 0.82 | HCAR2 (0.62) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL370268 | 0.79 | HCAR2 (0.69) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL859081 | 0.79 | HCAR2 (0.69) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL979497 | 0.79 | HCAR2 (0.74) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL7142763 | 0.79 | HCAR2 (0.74) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL979495 | 0.79 | HCAR2 (0.74) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL8104407 | 0.78 | MAPT (0.63) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL125126 | 0.77 | HCAR2 (1.00) | HCAR2MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL2561722 | 0.77 | HCAR2 (1.00) | HCAR2MAPTPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| EP-0275704-A1 | 1,2,4-Triazole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | HCAR2 4029/4885MAPT 1086/4885POLB 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.