Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 12/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium SCHEMBL30279498 | 0.83 | MAPT (0.62) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL1286940 | 0.81 | POLB (0.67) | MAPTNPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL1286936 | 0.81 | POLB (0.67) | MAPTNPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL7141083 | 0.81 | HCAR2 (0.67) | MAPTNPC1HTTRAB9AHCAR2 | |
| SCHEMBL7141082 | 0.81 | HCAR2 (0.67) | MAPTNPC1HTTRAB9AHCAR2 | |
| SCHEMBL11397919 | 0.80 | L3MBTL1 (0.63) | MAPTHCAR2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL1408805 | 0.80 | HCAR2 (0.65) | MAPTNPC1HTTRAB9AHCAR2 | |
| SCHEMBL7138125 | 0.79 | POLB (0.60) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7138121 | 0.79 | POLB (0.60) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7140021 | 0.79 | POLB (0.51) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513188-B | Coelenterazine analogs | 普洛麦格公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-113480545-A | Imidazopyrazinone compound and preparation method and application thereof | 山东大学 | 2021-10-08 | — | — | CN | disclosed |
| EP-0736031-B1 | IMPROVEMENTS IN OR RELATING TO CHIRAL SYNTHESES | OXFORD ASYMMETRY INTERNATIONAL (GB) | 2000-05-03 | — | — | EP | disclosed |
| US-6037498-A | Chiral syntheses | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 2000-03-14 | — | — | US | disclosed |
| EP-0736031-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL SYNTHESES | OXFORD ASYMMETRY LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018134-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL SYNTHESES | OXFORD ASYMMETRY LIMITED (GB) | 1995-07-06 | — | — | WO | disclosed |