Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704060 | 0.83 | WNT3A (0.52) | WNT3ATNKS2NPC1RAB9APOLB | |
| SCHEMBL10653820 | 0.83 | MEN1 (0.44) | WNT3ATNKS2NPC1RAB9APOLB | |
| SCHEMBL10653815 | 0.82 | WNT3A (0.48) | WNT3ATNKS2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10657811 | 0.81 | WNT3A (0.52) | WNT3ATNKS2RAB9APOLBHPGD | |
| SCHEMBL10658698 | 0.78 | WNT3A (0.55) | WNT3ATNKS2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL10712250 | 0.78 | WNT3A (0.55) | WNT3ATNKS2RAB9AHPGDALDH1A1 | |
| SCHEMBL10704054 | 0.77 | WNT3A (0.52) | WNT3ATNKS2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL10656139 | 0.74 | WNT3A (0.50) | WNT3ATNKS2RAB9APOLBSMN1; SMN2 | |
| SCHEMBL10654942 | 0.74 | ADRA2A (0.67) | WNT3ATNKS2RAB9AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10656331 | 0.73 | RAB9A (0.67) | WNT3ATNKS2RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183190-B1 | BENZAMIDES AND SALTS | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| US-4772630-A | ANTIDEPRESSANTS, ANTISCHIZOPHRENIA | CIBA-GEIGY CORP. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0183190-A1 | Benzamides and salts | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |