SCHEMBL10654034

SCHEMBL10654034

CCN(CC)c1ccc2cc(NF)c(C)cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.46
S100B P04271 1/20 0.45
MAPT P10636 8/20 0.42
LMNA P02545 4/20 0.42
HTT P42858 3/20 0.42
ESRRG P62508 1/20 0.41
RPS6KA2 Q15349 1/20 0.40
HSD17B10 Q99714 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 5/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
GLA P06280 2/20 0.40
KDM4E B2RXH2 2/20 0.40
GFER P55789 5/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAPK1 P28482 5/20 0.39
HCRTR1 O43613 1/20 0.39
NPSR1 Q6W5P4 3/20 0.39
ALOX15 P16050 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858562 0.81 S100B (0.52) TERTS100BMAPTLMNAHTT
SCHEMBL10990507 0.81 CYP2C19 (0.47) CYP2C19
SCHEMBL12288737 0.73 TERT (0.57) TERTS100BMAPTLMNAHTT
SCHEMBL18639364 0.72 CYP2A6 (0.56) TERTS100BMAPTLMNAHTT
SCHEMBL11438494 0.71 TERT (0.59) TERTS100BESRRGALDH1A1L3MBTL1
SCHEMBL29919654 0.71 TERT (0.59) TERTS100BESRRGALDH1A1L3MBTL1
SCHEMBL9066719 0.70 TERT (0.57) TERTS100BMAPTHTTESRRG
SCHEMBL4636720 0.69 S100B (0.59) TERTS100BMAPTLMNAHTT
SCHEMBL7770385 0.69 S100B (0.55) TERTS100BMAPTLMNAHTT
SCHEMBL3914779 0.69 S100B (0.55) TERTS100BMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089752-B1 FLUORAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN RECORDING SYSTEMS KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1988-04-20 EP disclosed
US-4524373-A Fluoran derivatives as new compounds, process for preparing the same and recording system utilizing the same as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-06-18 US disclosed
EP-0089752-A2 Fluoran derivatives, process for their preparation and their use in recording systems KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1983-09-28 EP disclosed