SCHEMBL6858562

SCHEMBL6858562

CCN(CC)c1ccc(C)c(NF)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.52
TERT O14746 1/20 0.44
ALDH1A1 P00352 8/20 0.41
MAPK1 P28482 6/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
CYP3A4 P08684 3/20 0.41
HSD17B10 Q99714 3/20 0.41
HPGD P15428 2/20 0.41
IGLV6-57 P01721 1/20 0.41
GLA P06280 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
ATM Q13315 1/20 0.41
HIF1A Q16665 1/20 0.41
MAPT P10636 8/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
RPS6KA2 Q15349 1/20 0.41
GFER P55789 5/20 0.41
PSMD14 O00487 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25400384 0.85 S100B (0.40) S100BTERTALDH1A1MAPK1L3MBTL1
SCHEMBL9659970 0.84 S100B (0.38) S100BTERTALDH1A1MAPK1L3MBTL1
SCHEMBL1262833 0.82 ALDH1A1 (0.38) S100BALDH1A1MAPTMEN1KMT2A
SCHEMBL10654034 0.81 TERT (0.46) S100BTERTALDH1A1MAPK1L3MBTL1
SCHEMBL30705197 0.81 ALDH1A1 (0.35) S100BALDH1A1L3MBTL1CYP3A4HPGD
SCHEMBL29162115 0.81 ALDH1A1 (0.35) S100BALDH1A1L3MBTL1CYP3A4HPGD
SCHEMBL3151654 0.79 ALDH1A1 (0.43) S100BTERTALDH1A1MAPK1L3MBTL1
SCHEMBL13741135 0.78 MAPT (0.48) S100BALDH1A1MAPK1L3MBTL1HSD17B10
SCHEMBL26418233 0.78 MAPT (0.48) S100BALDH1A1MAPK1L3MBTL1CYP3A4
SCHEMBL6013668 0.78 CYP2C19 (0.54) TSHRCYP2C19S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6784136-B2 RECORDING LAYER OF A FLUORAN BASED LEUCO DYE WITH MELTING POINT OF 190-230 DEGREES C AND N-P-TOLUENESULFONYL-N'-3-(P-TOLUENESULFONYLOXY) PHENYLUREA DEVELOPER, AND ALUMINUM HYDROXIDE, AMORPHOUS SILICA, KAOLIN OR TALC AS PIGMENTS OJI PAPER CO., LTD. (JP) 2004-08-31 US disclosed
EP-0375847-B1 Coating for pressure-sensitive recording sheets, and recording sheet having this coating JUJO PAPER CO LTD (JP) 1994-09-14 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
US-5013708-A Pressure-sensitive recording sheet and coating material therefor JUJO PAPER CO., LTD. (JP) 1991-05-07 US disclosed
EP-0160106-B1 PROCESS FOR MANUFACTURING COLOR-DEVELOPING SHEET FOR IMAGE-RECORDING MATERIAL MITSUBISHI PAPER MILLS, LTD. (JP) 1990-07-18 EP disclosed
US-4853361-A FLUORAN-TYPE LEUCO DYES JUJO PAPER CO., LTD. (JP) 1989-08-01 US disclosed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
EP-0160106-A1 PROCESS FOR MANUFACTURING COLOR-DEVELOPING SHEET FOR IMAGE-RECORDING MATERIAL MITSUBISHI PAPER MILLS, LTD. (JP) 1985-11-06 EP disclosed