Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | RORA | P35398 | 3/20 | 0.55 |
| ▸ | RORC | P51449 | 3/20 | 0.55 |
| ▸ | RORB | Q92753 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 12/20 | 0.52 |
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799854 | 0.87 | ALDH1A1 (0.55) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL13490798 | 0.84 | ALDH1A1 (0.51) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL27799843 | 0.83 | PGR (0.52) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL11681291 | 0.82 | ALDH1A1 (0.53) | PGRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL28174704 | 0.82 | CNR2 (0.58) | PGRRORARORCRORBALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27949259 | 0.81 | ALDH1A1 (0.52) | PGRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1335135 | 0.80 | PGR (0.73) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL29531665 | 0.80 | PGR (0.73) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL9657145 | 0.79 | PGR (0.54) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6013329 | 0.78 | KDM4E (0.59) | PGRRORARORCRORBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0243122-A3 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |