Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.66 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.66 |
| ▸ | BCHE | P06276 | 8/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651788 | 0.89 | ACHE (0.68) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10653196 | 0.84 | ACHE (0.70) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9207530 | 0.83 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEHRH3 | |
| SCHEMBL9583623 | 0.81 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10653208 | 0.77 | ACHE (0.58) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL4502500 | 0.77 | ACHE (0.62) | ACHEGRIN1GRIN2ABCHEHRH3 | |
| SCHEMBL9172294 | 0.72 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHECHRM1 | |
| SCHEMBL10654771 | 0.72 | ACHE (0.63) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10654307 | 0.72 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10652480 | 0.72 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |