Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.57 |
| ▸ | BCHE | P06276 | 8/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654771 | 0.92 | ACHE (0.63) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9208760 | 0.82 | ACHE (0.57) | ACHEGRIN1GRIN2ABCHELMNA | |
| SCHEMBL10654258 | 0.77 | ACHE (0.68) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL4506044 | 0.76 | ACHE (0.54) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10651092 | 0.74 | ACHE (0.62) | ACHEGRIN1GRIN2ABCHE | |
| SCHEMBL10651788 | 0.74 | ACHE (0.68) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10653394 | 0.74 | ACHE (0.64) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9583623 | 0.74 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL7282687 | 0.71 | ACHE (0.52) | ACHEGRIN1GRIN2ABCHEPARP1 | |
| SCHEMBL28700551 | 0.69 | ACHE (0.56) | ACHEGRIN1GRIN2ABCHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |