Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.70 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.46 |
| ▸ | BCHE | P06276 | 7/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654258 | 0.84 | ACHE (0.68) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9039832 | 0.82 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9207530 | 0.81 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHE | |
| SCHEMBL10653394 | 0.75 | ACHE (0.64) | ACHEDCPSGRIN1GRIN2ABCHE | |
| SCHEMBL4502500 | 0.75 | ACHE (0.62) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10651788 | 0.73 | ACHE (0.68) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL28984974 | 0.71 | ACHE (0.66) | ACHEDCPSGRIN1GRIN2ABCHE | |
| SCHEMBL10654307 | 0.70 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL10652480 | 0.70 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9583526 | 0.70 | ACHE (1.00) | ACHEDCPSGRIN1GRIN2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |