Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654025 | 0.78 | NQO2 (0.40) | CYP1A2KDM4EALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL13030159 | 0.69 | CRBN (0.45) | — | |
| SCHEMBL10655874 | 0.68 | CRBN (0.41) | ALDH1A1MAPTGAA | |
| SCHEMBL10656570 | 0.68 | CRBN (0.41) | ALDH1A1MAPTGAA | |
| SCHEMBL10652269 | 0.67 | MEN1 (0.41) | KDM4EALDH1A1HSD17B10MAPTGRIN2D | |
| Hydrochloric Acid SCHEMBL10651039 | 0.66 | MEN1 (0.40) | KDM4EALDH1A1HSD17B10CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL10651036 | 0.66 | MEN1 (0.40) | KDM4EALDH1A1HSD17B10CYP3A4MAPT | |
| SCHEMBL10653826 | 0.65 | CRBN (0.41) | CYP1A2MAPTPDE3BPDE3A | |
| SCHEMBL10655308 | 0.64 | MAPT (0.39) | KDM4EALDH1A1PKMMAPTMPI | |
| SCHEMBL10655304 | 0.64 | MAPT (0.39) | KDM4EALDH1A1PKMMAPTMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |