SCHEMBL13030159

SCHEMBL13030159

CO/N=c1\cc[nH]c(=O)[nH]1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.45
▸ MMP2 P08253 1/20 0.43
▸ TYMP P19971 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N4-Hydroxycytosine SCHEMBL13071713 0.72 — —
N4-Hydroxycytosine SCHEMBL24574318 0.72 — —
SCHEMBL10654025 0.70 NQO2 (0.40) CRBNMMP2
SCHEMBL10653826 0.68 CRBN (0.41) CRBNMMP2
SCHEMBL10652272 0.67 MEN1 (0.41) CRBNMMP2
SCHEMBL10653786 0.66 PTGS2 (0.42) CRBNMMP2
SCHEMBL10656570 0.64 CRBN (0.41) CRBNMMP2
SCHEMBL10655874 0.64 CRBN (0.41) CRBNMMP2
Uracil SCHEMBL11607890 0.63 — —
Uracil SCHEMBL5089507 0.63 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094863-B1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES, PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME PANAGENE INC (KR) 2014-08-06 — — EP disclosed
US-20100292471-A1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME PANAGENE INC. (KR) 2010-11-18 — — US disclosed
US-20080233557-A1 PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses PANAGENE INC. (KR) 2008-09-25 — — US disclosed
US-20080233557-A1 PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses PANAGENE INC. (KR) 2008-09-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080233557-A1 PNA Probes, Kits, and Methods for Detecting Lamivudine-Resistant Hepatitis B Viruses POLM, RNPEP, PNP CRBN 3279/4885MMP2 1950/4885TYMP 5/4885
US-20100292471-A1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME ADAR, POLM, POLRMT CRBN 3365/4885MMP2 2705/4885TYMP 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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