Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654310 | 0.78 | TUBB4A (0.37) | NQO2PDE3BPDE3AALDH1A1CYP3A4 | |
| SCHEMBL10652269 | 0.71 | MEN1 (0.41) | ALDH1A1CRBNKDM4EHSD17B10LMNA | |
| SCHEMBL10652272 | 0.71 | MEN1 (0.41) | ALDH1A1CRBNKDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL10651036 | 0.70 | MEN1 (0.40) | ALDH1A1CYP3A4HPGDCRBNKDM4E | |
| Hydrochloric Acid SCHEMBL10651039 | 0.70 | MEN1 (0.40) | ALDH1A1CYP3A4HPGDCRBNKDM4E | |
| SCHEMBL13030159 | 0.70 | CRBN (0.45) | CRBNMMP2 | |
| SCHEMBL10653826 | 0.69 | CRBN (0.41) | PDE3BPDE3ACYP1A2CRBNMMP2 | |
| SCHEMBL7291800 | 0.67 | NQO2 (0.50) | NQO2PDE3BPDE3AABCG2ALDH1A1 | |
| SCHEMBL1748919 | 0.66 | MEN1 (0.48) | NQO2PDE3BPDE3AALDH1A1CYP3A4 | |
| SCHEMBL14671417 | 0.65 | HSD17B10 (0.45) | NQO2PDE3BPDE3AABCG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |