Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568592 | 0.72 | KDM4E (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL1530327 | 0.72 | CRBN (0.47) | CYP2C9CYP1A2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL940939 | 0.72 | MAPT (0.49) | CYP2C9CYP1A2L3MBTL1MAPTKDM4E | |
| SCHEMBL9529067 | 0.70 | CYP1A2 (0.60) | CYP2C9CYP1A2L3MBTL1MAPTGAA | |
| SCHEMBL26684027 | 0.70 | CRBN (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11250852 | 0.70 | L3MBTL1 (0.70) | CYP2C9CYP1A2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11356906 | 0.69 | CYP2C9 (0.64) | CYP2C9CYP1A2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL15207389 | 0.69 | CRBN (0.44) | CYP2C9CYP1A2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL28744560 | 0.68 | CRBN (0.59) | L3MBTL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10565535 | 0.67 | KDM4E (0.52) | MAPTALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |