Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779546 | 0.83 | CYP2C9 (0.48) | CYP2C9BRD9GAAMAPK1NTRK1 | |
| SCHEMBL8187626 | 0.76 | CYP2C9 (0.74) | CYP2C9BRD9GAAMAPK1LMNA | |
| SCHEMBL28904576 | 0.75 | ALDH1A1 (0.56) | CYP2C9BRD9MAPK1LMNANTRK1 | |
| SCHEMBL30615640 | 0.75 | ALDH1A1 (0.56) | CYP2C9BRD9MAPK1LMNANTRK1 | |
| SCHEMBL9472940 | 0.75 | ATM (0.57) | GAALMNANTRK1IGF1RFGFR1 | |
| SCHEMBL3030044 | 0.74 | CYP1A2 (0.64) | GAANTRK1IGF1RFGFR1NTRK2 | |
| SCHEMBL11351513 | 0.72 | G6PD (0.74) | CYP2C9BRD9GAAMAPK1LMNA | |
| SCHEMBL10430351 | 0.70 | TUBB4A (0.51) | CYP2C9BRD9GAAMAPK1LMNA | |
| SCHEMBL12962502 | 0.70 | LMNA (0.73) | CYP2C9BRD9GAAMAPK1LMNA | |
| SCHEMBL7663784 | 0.70 | GAA (0.52) | CYP2C9BRD9GAAMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033503-A2 | Medicaments with cytostatic activity and use of cyclic compounds, in which the heterocyclic N-ring atoms are substituted by several glycidyl groups, in pharmaceutical compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-08-12 | — | — | EP | disclosed |