Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535853 | 0.87 | CYP1A2 (0.47) | CYP1A2L3MBTL1F10MAPTGAA | |
| SCHEMBL29132992 | 0.85 | CYP1A2 (0.46) | CYP1A2L3MBTL1F10MAPTCYP2C9 | |
| SCHEMBL8160058 | 0.85 | CYP1A2 (0.46) | CYP1A2L3MBTL1F10MAPTGAA | |
| SCHEMBL12545383 | 0.83 | CYP1A2 (0.43) | CYP1A2L3MBTL1F10MAPTGAA | |
| SCHEMBL8149820 | 0.82 | PDE5A (0.46) | CYP1A2L3MBTL1F10MAPTCYP2C9 | |
| SCHEMBL28328775 | 0.82 | ALDH1A1 (0.49) | CYP1A2L3MBTL1F10 | |
| SCHEMBL8148718 | 0.82 | CYP1A2 (0.43) | CYP1A2L3MBTL1F10MAPTGAA | |
| SCHEMBL8164439 | 0.81 | ALDH1A1 (0.57) | CYP1A2L3MBTL1F10LMNAMAPT | |
| SCHEMBL14009316 | 0.78 | CYP1A2 (0.40) | CYP1A2L3MBTL1F10CYP2C9 | |
| SCHEMBL18050078 | 0.77 | MGLL (0.54) | CYP1A2MAPTTP53FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |