SCHEMBL1065455

SCHEMBL1065455

C=CC(=O)OCCC[Si](C)(OCCC)OCCC

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
HPGD P15428 1/20 0.61
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.42
THRB P10828 4/20 0.41
HCAR2 Q8TDS4 4/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140135 0.92 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1064310 0.90 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29964835 0.89 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL108297 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL7990755 0.88 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8900975 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL3440898 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29965212 0.86 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL231020 0.86 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL949700 0.85 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US claimed
US-20260139100-A1 RESIN COMPOSITION CONTAINING SILICONE-VINYL ACETATE COPOLYMER RESIN, AND METHOD FOR PRODUCING SAME NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 2026-05-21 US disclosed
EP-3898810-B1 ADHESIVE WITH HIGH FILLER CONTENT AVERY DENNISON CORP (US) 2025-12-03 EP disclosed
US-12435240-B2 Coating composition for an outer wall or exterior of building, and an article comprising the coating composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 2025-10-07 US disclosed
EP-4615884-A1 PROCESS FOR FORMING AN AQUEOUS DISPERSION OF COPOLYMERS, AN ADHESIVE COMPOSITION INCLUDING SUCH COPOLYMERS, A FILM OR AN ARTICLE COMPRISING THE SAME, AND A METHOD OF COATING A SUBSTRATE Wacker Chemie AG (DE) 2025-09-17 EP disclosed
US-20250270410-A1 INK COMPOSITION FOR AN INKJET, A RECORDED MATERIAL, AND A RECORDING METHOD WITH AN INKJET NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 2025-08-28 US disclosed
EP-4588984-A1 AQUEOUS INK COMPOSITION Kaneka Corporation (JP) 2025-07-23 EP disclosed
US-20250206969-A1 AQUEOUS INK COMPOSITION KANEKA CORPORATION (JP) 2025-06-26 US disclosed
EP-0695783-B1 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR (JP) 2000-02-02 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
US-5650475-A VINYL POLYMERS WITH BLOCKED CARBOXY, SILANOL, EPOXY, HYDROLYZED SILYL AND ACID ANHYDRIDES IN SOLVENTS MAZDA MOTOR CORPORATION (JP) 1997-07-22 US disclosed
EP-0695783-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition Mazda Motor Corporation (JP) 1996-02-07 EP disclosed
EP-0688841-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR CORPORATION (JP) 1995-12-27 EP disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139100-A1 RESIN COMPOSITION CONTAINING SILICONE-VINYL ACETATE COPOLYMER RESIN, AND METHOD FOR PRODUCING SAME ITGA1, COL1A1, ITGB1 TSHR 2691/4885HPGD 2858/4885ALDH1A1 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.