SCHEMBL3440898

SCHEMBL3440898

C=CC(=O)OCCC[Si](C)(C)OCCC

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
HPGD P15428 1/20 0.61
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.42
THRB P10828 4/20 0.41
HCAR2 Q8TDS4 4/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22115841 0.92 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29965104 0.89 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL107693 0.89 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1065455 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8900975 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29965478 0.86 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL229125 0.86 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL949700 0.85 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL946740 0.85 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16536923 0.84 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050244658-A1 Inorganic/organic hybrid oligomer and nano hybrid polymer for use in optical devices and displays, and process for preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-11-03 US claimed
CN-120077081-A Epoxy resin composition 三键有限公司 2025-05-30 CN disclosed
WO-2024262261-A1 EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF 株式会社スリーボンド 2024-12-26 WO disclosed
CN-115279817-B Epoxy resin composition 三键有限公司 2024-08-23 CN disclosed
US-20240279441-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-08-22 US disclosed
CN-118146724-A Curable resin composition, cured product, laminate comprising cured product, and method for disassembling laminate 三键有限公司 2024-06-07 CN disclosed
EP-4349902-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
CN-112585181-B Curable resin composition and cured product 三键有限公司 2024-01-30 CN disclosed
CN-117377722-A Rubber composition and tire 株式会社普利司通 2024-01-09 CN disclosed
CN-117242134-A Curable resin composition 三键有限公司 2023-12-15 CN disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-8299185-B2 Curable cage-type silicone copolymer and process for production thereof and curable resin composition comprising curable cage-type silicone copolymer and cured product thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20100280190-A1 CURABLE CAGE-TYPE SILICONE COPOLYMER AND PROCESS FOR PRODUCTION THEREOF AND CURABLE RESIN COMPOSITION COMPRISING CURABLE CAGE-TYPE SILICONE COPOLYMER AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-11-04 US disclosed
US-7813615-B2 Flexible film optical waveguide using organic-inorganic hybrid material and fabrication method thereof KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-10-12 US disclosed
US-20090052856-A1 Flexible Film Optical Waveguide Using Organic-Inorganic Hybrid Material and Fabrication Method Thereof KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-02-26 US disclosed
EP-1818186-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-15 EP disclosed
WO-2006112592-A1 FLEXIBLE FILM OPTICAL WAVEGUIDE USING ORGANIC-INORGANIC HYBRID MATERIAL AND FABRICATION METHOD THEREOF KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2006-10-26 WO disclosed
US-20050244658-A1 Inorganic/organic hybrid oligomer and nano hybrid polymer for use in optical devices and displays, and process for preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-11-03 US disclosed
US-6747095-B2 CONJUGATED DIENE UNIT, AROMATIC VINYL UNIT, MONOMER UNIT HAVING TWO POLYMERIZABLE UNSATURATED GROUPS, MONOMER UNIT HAVING ONE POLYMERIZABLE UNSATURATED GROUP; DIMENSIONAL STABILITY JSR CORPORATION (JP) 2004-06-08 US disclosed
US-20020007011-A1 Crosslinked rubber particles and rubber compositions JSR CORPORATION (JP) 2002-01-17 US disclosed