Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654942 | 0.85 | ADRA2A (0.67) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10655240 | 0.84 | ADRA2A (0.54) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| Hydrochloric Acid SCHEMBL10656331 | 0.84 | RAB9A (0.67) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| Hydrochloric Acid SCHEMBL10657760 | 0.83 | RAB9A (0.54) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10656903 | 0.82 | ADRA2A (0.70) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10705150 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10656871 | 0.82 | ADRA2A (0.52) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| Hydrochloric Acid SCHEMBL10660028 | 0.81 | RAB9A (0.71) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10656321 | 0.80 | ADRA2A (0.49) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 | |
| SCHEMBL10656342 | 0.80 | ADRA2A (0.49) | ALDH1A1CYP1A2ADRA2ACYP2D6DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183190-B1 | BENZAMIDES AND SALTS | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| US-4772630-A | ANTIDEPRESSANTS, ANTISCHIZOPHRENIA | CIBA-GEIGY CORP. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0183190-A1 | Benzamides and salts | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |