Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072722 | 0.79 | HSD11B1 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL28402747 | 0.79 | HSD11B1 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL28402748 | 0.79 | HSD11B1 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL9702100 | 0.79 | CA1 (0.55) | CA2CA1CA12CA9CA14 | |
| SCHEMBL30423587 | 0.78 | SLC1A3 (0.52) | CA2CA1CA12CA9CA14 | |
| SCHEMBL7868823 | 0.78 | SLC1A3 (0.52) | CA2CA1CA12CA9CA14 | |
| SCHEMBL12237253 | 0.78 | ALDH1A1 (0.53) | CA2CA1CA12CA9CA14 | |
| SCHEMBL4253160 | 0.78 | CA2 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL19126866 | 0.78 | CA2 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL19970090 | 0.77 | MAPT (0.47) | CA2CA1CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184660-B1 | MONOCYCLIC BIS-OXYETHYLSULFONYL-BENZENES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-06 | — | — | EP | disclosed |
| EP-0184660-A1 | Monocyclic bis-oxyethylsulfonyl-benzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-18 | — | — | EP | disclosed |