Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101107 | 0.99 | RAB9A (0.55) | RAB9AMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL2485756 | 0.93 | TDP1 (0.58) | RAB9AMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL2483050 | 0.92 | TDP1 (0.64) | RAB9AMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL1101056 | 0.92 | HRH3 (0.58) | RAB9AMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL2486394 | 0.90 | HRH3 (0.64) | RAB9AMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL1100987 | 0.87 | PIK3CD (0.53) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL1101288 | 0.86 | PIK3CD (0.52) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL10656768 | 0.81 | HTR7 (0.62) | HTR1ADRD2HTR2CHTR7DRD3 | |
| SCHEMBL4141493 | 0.81 | TDP1 (0.56) | LMNASMN1; SMN2TDP1ADRB2HTR1A | |
| SCHEMBL2486100 | 0.81 | RAB9A (0.52) | RAB9AMAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-4735943-A | VASODILATORS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0168197-A2 | Eburnamonine oxime derivatives and their preparation and pharmaceutical compositions containing them | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |