Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 6/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723284 | 0.84 | DRD2 (0.72) | HTR7DRD2HTR1AHTR2AABCB1 | |
| SCHEMBL10660481 | 0.81 | MAPT (0.76) | DRD2SLC6A2SLC6A4HTR1AHTR2A | |
| SCHEMBL10654773 | 0.81 | RAB9A (0.56) | HTR7DRD2HTR1ADRD3HTR2C | |
| SCHEMBL1101107 | 0.80 | RAB9A (0.55) | HTR7HTR6DRD2HTR1AHTR2A | |
| SCHEMBL11827962 | 0.79 | DRD3 (0.70) | HTR7DRD2SLC6A2SLC6A4HTR1A | |
| SCHEMBL9826331 | 0.79 | DRD3 (0.70) | HTR7DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1100987 | 0.78 | PIK3CD (0.53) | HTR7DRD2HTR1ADRD3HTR2C | |
| SCHEMBL9826692 | 0.77 | DRD2 (0.55) | HTR7HTR6DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL1101288 | 0.77 | PIK3CD (0.52) | HTR7DRD2HTR1ADRD3HTR2C | |
| SCHEMBL8720336 | 0.76 | ALDH1A1 (0.72) | HTR7DRD2SLC6A2SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735943-A | VASODILATORS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-04-05 | — | — | US | claimed |
| US-4735943-A | VASODILATORS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |