SCHEMBL10654872

SCHEMBL10654872

CCOC(=O)C(C)(O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.55
TSHR P16473 2/20 0.55
ABCB11 O95342 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
HTR2A P28223 1/20 0.55
PMP22 Q01453 1/20 0.55
PIN1 Q13526 1/20 0.50
MMP8 P22894 1/20 0.48
PPARG P37231 4/20 0.47
POLB P06746 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
FBP1 P09467 2/20 0.45
ALDH1A1 P00352 1/20 0.44
RECQL P46063 1/20 0.44
OPRK1 P41145 1/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
CRHBP P24387 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2824491 0.88 PPARA (0.71) PPARATSHRABCB11CYP1A2CYP3A4
Phenol SCHEMBL4706535 0.82 PPARA (0.63) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL28230446 0.81 PIN1 (0.49) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL11358611 0.81 OPRK1 (0.63) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL8468475 0.80 KCNN4 (0.50) PPARATSHRCYP1A2CYP3A4PPARG
SCHEMBL28644949 0.80 KCNN4 (0.50) PPARATSHRCYP1A2CYP3A4PPARG
SCHEMBL12913900 0.80 PPARA (0.49) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL24497220 0.79 POLB (0.50) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL27352386 0.79 TSHR (0.51) PPARATSHRABCB11CYP1A2CYP3A4
SCHEMBL6377517 0.79 NPC1 (0.54) PPARATSHRABCB11CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4767880-A WITH ALKALI METAL ALCOHOLATE, PHENOLATE, HYDROXYPHENOXYPROPIONATE OR HYDROQUINONE SALT HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-30 US disclosed