Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | BHMT | Q93088 | 1/20 | 0.30 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.30 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653648 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9SLC7A5NOS2 | |
| SCHEMBL10654701 | 0.81 | DPP4 (0.38) | DPP4DPP8DPP9SLC7A5NOS2 | |
| SCHEMBL10943106 | 0.76 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL27262388 | 0.76 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL17100549 | 0.76 | DPP7 (0.50) | DPP4DPP8DPP9DPP7SLC15A1 | |
| SCHEMBL10658481 | 0.75 | GLO1 (0.39) | DPP4DPP8DPP9 | |
| SCHEMBL10703971 | 0.73 | DPP7 (0.51) | DPP4DPP8DPP9DPP7SLC15A1 | |
| SCHEMBL10655332 | 0.73 | GSR (0.48) | NOS2NOS3NOS1BHMTBHMT2 | |
| SCHEMBL10657081 | 0.73 | GSR (0.48) | NOS2NOS3NOS1BHMTBHMT2 | |
| SCHEMBL8525692 | 0.73 | DPP4 (0.40) | DPP4DPP8DPP9SLC7A5BHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730006-A | BACTERICIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-08 | — | — | US | disclosed |