Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654701 | 0.88 | DPP4 (0.38) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL10653648 | 0.84 | DPP4 (0.40) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL14359921 | 0.79 | DPP4 (0.58) | GLO1PTGS1GSTK1ALDH1A1LMNA | |
| SCHEMBL14359927 | 0.76 | DPP4 (0.55) | GLO1PTGS1GSTK1ALDH1A1LMNA | |
| SCHEMBL31064905 | 0.76 | ALDH1A1 (0.44) | PTGS1GSTK1ALDH1A1LMNAMAPT | |
| SCHEMBL2740066 | 0.75 | ALDH1A1 (0.47) | GLO1PTGS1GSTK1ALDH1A1LMNA | |
| SCHEMBL14031342 | 0.75 | MME (0.49) | GLO1PTGS1GSTK1ALDH1A1LMNA | |
| SCHEMBL30552957 | 0.75 | ALDH1A1 (0.47) | GLO1PTGS1GSTK1ALDH1A1LMNA | |
| SCHEMBL29514286 | 0.75 | DPP8 (0.48) | PTGS1GSTK1ALDH1A1LMNAMAPT | |
| SCHEMBL30052913 | 0.75 | METAP2 (0.43) | GLO1PTGS1GSTK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730006-A | BACTERICIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-08 | — | — | US | disclosed |