Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655093 | 1.00 | PPARG (0.50) | PPARGPPARAACEMEN1KMT2A | |
| SCHEMBL12198216 | 0.86 | CA2 (0.52) | PPARGPPARAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2806085 | 0.86 | ALDH1A1 (0.50) | PPARGPPARAACECA2CA1 | |
| SCHEMBL2806082 | 0.86 | ALDH1A1 (0.50) | PPARGPPARAACECA2CA1 | |
| SCHEMBL10659527 | 0.85 | CA2 (0.54) | PPARGPPARAACEKMT2ACA2 | |
| SCHEMBL10659530 | 0.85 | CA2 (0.54) | PPARGPPARAACEKMT2ACA2 | |
| SCHEMBL11657971 | 0.83 | GAA (0.50) | MEN1KMT2ASMN1; SMN2CA2CA1 | |
| SCHEMBL1640055 | 0.82 | CA2 (0.66) | CA2CA1HPGDLMNA | |
| SCHEMBL8379946 | 0.82 | CA2 (0.66) | CA2CA1HPGDLMNA | |
| SCHEMBL6739798 | 0.81 | ACE (0.62) | PPARGPPARAACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |