Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 20/20 | 0.45 |
| ▸ | BCHE | P06276 | 13/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652494 | 0.90 | ACHE (0.43) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9172294 | 0.78 | ACHE (0.66) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9164979 | 0.78 | ACHE (0.66) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10654658 | 0.78 | ACHE (0.43) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10650942 | 0.75 | ACHE (0.41) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9171950 | 0.73 | TNKS (0.46) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL4502500 | 0.72 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9207530 | 0.70 | ACHE (0.66) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10654258 | 0.70 | ACHE (0.68) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL25489688 | 0.69 | ACHE (0.69) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |