Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584636 | 0.80 | CA1 (0.33) | CA1CA2CA4 | |
| SCHEMBL7152606 | 0.74 | ADRA2C (0.50) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL10654516 | 0.74 | CA1 (0.32) | CA1CA2CA4 | |
| SCHEMBL3199864 | 0.72 | ADRB2 (0.31) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL1996784 | 0.70 | MEN1 (0.37) | CA1CA2CA4 | |
| SCHEMBL10582030 | 0.69 | — | — | |
| SCHEMBL9584176 | 0.69 | — | — | |
| SCHEMBL27372519 | 0.67 | CA1 (0.33) | CA1CA2CA4 | |
| SCHEMBL10581878 | 0.66 | CA1 (0.31) | CA1CA2CA4 | |
| SCHEMBL9003976 | 0.64 | CA1 (0.33) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |