Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652008 | 0.87 | SLC10A6 (0.46) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL8661200 | 0.77 | TDP1 (0.58) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL10656087 | 0.76 | KMT2A (0.50) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL9620989 | 0.76 | TDP1 (0.57) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL563639 | 0.76 | TDP1 (0.57) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL10570435 | 0.75 | ALDH1A1 (0.48) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL10873626 | 0.74 | SLC10A6 (0.43) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL5638270 | 0.74 | CA1 (0.59) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL11527174 | 0.74 | CA1 (0.59) | L3MBTL1TDP1THRBCA1CA2 | |
| SCHEMBL5638275 | 0.74 | CA1 (0.59) | L3MBTL1TDP1THRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197386-B1 | 2-(SUBSTITUTED SULFAMYL) DERIVATIVES OF 6-NITROBENZOIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1988-11-02 | — | — | EP | claimed |