Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656976 | 0.88 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1CA12CYP19A1 | |
| SCHEMBL10568780 | 0.87 | NPY5R (0.49) | KMT2AMEN1ALDH1A1CA12TDP1 | |
| SCHEMBL10565319 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1CA12TDP1 | |
| SCHEMBL10570435 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1CA12TDP1 | |
| SCHEMBL10569654 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1CA12L3MBTL1 | |
| SCHEMBL454129 | 0.83 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1CA12TDP1 | |
| SCHEMBL9620317 | 0.80 | PKM (0.56) | KMT2AMEN1ALDH1A1L3MBTL1CYP2C19 | |
| SCHEMBL10571766 | 0.79 | NPY5R (0.46) | KMT2AMEN1ALDH1A1CA12TDP1 | |
| SCHEMBL9811375 | 0.79 | KMT2A (0.46) | KMT2AMEN1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10572547 | 0.78 | NPY5R (0.45) | KMT2AMEN1ALDH1A1CA12CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197386-B1 | 2-(SUBSTITUTED SULFAMYL) DERIVATIVES OF 6-NITROBENZOIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1988-11-02 | — | — | EP | claimed |