Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9811310 | 0.90 | KMT2A (0.43) | KMT2AMEN1NPY5RKDM4ELMNA | |
| SCHEMBL9811288 | 0.89 | KMT2A (0.44) | KMT2AMEN1NPY5RKDM4ELMNA | |
| SCHEMBL9811304 | 0.88 | KMT2A (0.43) | KMT2AMEN1NPY5RKDM4ELMNA | |
| SCHEMBL9620317 | 0.87 | PKM (0.56) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL9811328 | 0.84 | KMT2A (0.43) | KMT2AMEN1NPY5RKDM4ELMNA | |
| SCHEMBL9811280 | 0.82 | ALDH1A1 (0.39) | KMT2AMEN1KDM4ELMNAGAA | |
| SCHEMBL9620614 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL9811320 | 0.80 | KMT2A (0.41) | KMT2AMEN1NPY5RKDM4ELMNA | |
| SCHEMBL10656087 | 0.79 | KMT2A (0.50) | KMT2AMEN1NPY5RLMNAMAPT | |
| SCHEMBL10735758 | 0.78 | SMN1; SMN2 (0.47) | KMT2AMEN1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223124-B1 | SUBSTITUTED AMINOSULFONYL 6-NITROBENZOIC-ESTERS OR AMIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | claimed |