Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336314 | 0.88 | ADRB1 (0.68) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL9802700 | 0.88 | ADRB1 (0.68) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL13148891 | 0.85 | ADRB1 (0.78) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11194692 | 0.83 | ADRB1 (0.74) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| Carteolol SCHEMBL24810 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1CYP1A2 | |
| Carteolol SCHEMBL24811 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1CYP1A2 | |
| Carteolol SCHEMBL146637 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1CYP1A2 | |
| SCHEMBL11272012 | 0.82 | ADRB1 (0.61) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| Carteolol SCHEMBL2549082 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1CYP1A2 | |
| SCHEMBL11547677 | 0.82 | ADRB1 (0.70) | ADRB1ADRB2HTR1AOPRK1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065456-A | CNS DEPRESSANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1977-12-27 | — | — | US | claimed |
| JP-57169463-A | — | — | None | — | — | JP | disclosed |
| EP-0273987-A1 | PROCESS FOR PREPARING TETRAHYDROQUINOLONE ETHERS AND NOVEL INTERMEDIATES THEREFOR | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-07-13 | — | — | EP | disclosed |
| JP-S57169463-A | PREPARATION OF CARBOSTYRIL DERIVATIVE | OTA SEIYAKU KK | 1982-10-19 | — | — | JP | disclosed |
| US-4065456-A | CNS DEPRESSANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1977-12-27 | — | — | US | disclosed |