Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carteolol SCHEMBL146637 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| Carteolol SCHEMBL24811 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| Carteolol SCHEMBL24810 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| Carteolol SCHEMBL29908301 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| Carteolol SCHEMBL30872857 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| SCHEMBL11272012 | 0.82 | ADRB1 (0.61) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| Carteolol SCHEMBL2549082 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| SCHEMBL10656269 | 0.82 | ADRB1 (0.69) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| Carteolol SCHEMBL41380 | 0.81 | ADRB2 (0.98) | ADRB1ADRB2HTR1AOPRK1ADRB3 | |
| Carteolol SCHEMBL41382 | 0.81 | ADRB2 (0.98) | ADRB1ADRB2HTR1AOPRK1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |