Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547677 | 0.82 | ADRB1 (0.70) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL10656269 | 0.82 | ADRB1 (0.69) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL9802700 | 0.81 | ADRB1 (0.68) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL9336314 | 0.81 | ADRB1 (0.68) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL11280720 | 0.79 | DRD2 (0.46) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL11273318 | 0.79 | ADRB1 (0.60) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL11282768 | 0.78 | ADRB1 (0.59) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL13148891 | 0.78 | ADRB1 (0.78) | ADRB1ADRB2HTR1AOPRK1SCN5A | |
| SCHEMBL11283387 | 0.77 | MAOA (0.58) | HTR1ADRD2DRD4DRD3BACE1 | |
| SCHEMBL11194692 | 0.76 | ADRB1 (0.74) | ADRB1ADRB2HTR1AOPRK1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |