Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943353 | 1.00 | RAB9A (0.59) | RAB9AALDH1A1CTSLHPGDPRSS1 | |
| SCHEMBL27306278 | 0.83 | ALDH1A1 (0.49) | RAB9AALDH1A1CTSLHPGDCTRB1 | |
| SCHEMBL10921235 | 0.83 | ALDH1A1 (0.52) | RAB9AALDH1A1NPC1SMN1; SMN2MEN1 | |
| SCHEMBL10921240 | 0.83 | ALDH1A1 (0.52) | RAB9AALDH1A1NPC1SMN1; SMN2MEN1 | |
| SCHEMBL6841169 | 0.80 | RAB9A (0.61) | RAB9AALDH1A1CTSLHPGDPRSS1 | |
| SCHEMBL16225033 | 0.80 | RAB9A (0.61) | RAB9AALDH1A1CTSLHPGDPRSS1 | |
| SCHEMBL8526512 | 0.80 | RAB9A (0.87) | RAB9AALDH1A1HPGDPRSS1CTSG | |
| SCHEMBL799431 | 0.80 | RAB9A (0.87) | RAB9AALDH1A1HPGDPRSS1CTSG | |
| SCHEMBL8507346 | 0.80 | RAB9A (0.87) | RAB9AALDH1A1HPGDPRSS1CTSG | |
| SCHEMBL8742306 | 0.79 | ACACB (0.50) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0074761-B1 | PEPTIDE-TYPE SUBSTRATES USEFUL IN THE QUANTITATIVE DETERMINATION OF ENDOTOXIN | WHITTAKER CORPORATION (US) | 1985-12-27 | — | — | EP | disclosed |