Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.87 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507346 | 1.00 | RAB9A (0.87) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL799431 | 1.00 | RAB9A (0.87) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL29137460 | 0.86 | RAB9A (0.67) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL1003282 | 0.85 | RAB9A (0.82) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3380039 | 0.85 | RAB9A (0.65) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL12019757 | 0.85 | RAB9A (0.65) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14115136 | 0.85 | ALDH1A1 (0.70) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24175853 | 0.83 | ALDH1A1 (0.68) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4821933 | 0.83 | RAB9A (0.63) | RAB9AALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL22901903 | 0.83 | RAB9A (0.63) | RAB9AALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046403-A1 | NOVEL PROCESS FOR THE PREPARATION OF ENANTIOPURE 3- ENANTIOPURE 3-AMINO TETRAHYDROFURAN AND ITS SALTS | MAJEED MUHAMMED (US) | 2020-03-05 | — | — | WO | disclosed |
| EP-0934264-A1 | PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS | PFIZER INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998012177-A1 | PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS | PFIZER INC. (JP) | 1998-03-26 | — | — | WO | disclosed |