Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931049 | 1.00 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL42290 | 0.77 | — | — | |
| SCHEMBL16469538 | 0.77 | — | — | |
| SCHEMBL4985635 | 0.75 | LMNA (0.53) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL9634213 | 0.75 | — | — | |
| SCHEMBL3626089 | 0.75 | — | — | |
| SCHEMBL10656856 | 0.74 | LMNA (0.40) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL10656861 | 0.74 | LMNA (0.40) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL8962571 | 0.73 | LMNA (0.67) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL28389547 | 0.73 | LMNA (0.67) | LMNABLMPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |