SCHEMBL10656399

SCHEMBL10656399

CC(C)=CC(=O)COc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
MTNR1A P48039 3/20 0.46
MTNR1B P49286 3/20 0.46
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 1/20 0.45
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31172364 0.79 ALOX15 (0.63) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL7746 0.78 ALOX15 (0.68) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL11367180 0.77 ALOX15 (0.61) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL5497407 0.77 ALOX15 (0.61) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL19783265 0.77 ALOX15 (0.61) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL11008229 0.77 ALOX15 (0.61) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL19305271 0.73 ALOX15 (0.60) ALOX15SMN1; SMN2KMT2AMEN1ALPL
SCHEMBL27386501 0.73 ALOX15 (0.60) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL97376 0.73 ALOX15 (0.60) ALOX15SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL8127 0.73 ALOX15 (1.00) ALOX15SMN1; SMN2KMT2AMEN1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365722-B2 Routes to trans A,B-substituted bacteriochlorins NORTH CAROLINA STATE UNIVERSITY (US) 2016-06-14 US disclosed
US-20140221644-A1 NEW ROUTES TO TRANS A,B-SUBSTITUTED BACTERIOCHLORINS UNITED STATES DEPARTMENT OF ENERGY 2014-08-07 US disclosed
WO-2013062670-A2 NEW ROUTES TO TRANS A,B-SUBSTITUTED BACTERIOCHLORINS NORTH CAROLINA STATE UNIVERSITY (US) 2013-05-02 WO disclosed
US-4749814-A CATALYTIC ISOMERIZATION OF ACETYLENIC ALCOHOLS RHONE-POULENC SANTE (FR) 1988-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221644-A1 NEW ROUTES TO TRANS A,B-SUBSTITUTED BACTERIOCHLORINS CTH, HBS1L, EBPL ALOX15 4345/4885SMN1; SMN2 4438/4885KMT2A 3658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.